Center for Human Aging and Performance

Studying How Well People Age

The Center for Human Aging and Performance is a new initiative by Maragin Health Foundation focused on measuring, understanding, and improving functional aging. Aging is not defined by time alone. Two people may both be 80 years old, but one may walk independently, think clearly, and live actively, while another struggles with mobility, strength, and daily function.

How well is a person aging?

CHAP was created to answer this simple but important question. Rather than focusing only on disease or chronological age, CHAP focuses on function: how well people move, think, recover, remain independent, and maintain quality of life.


Why It Matters

Standardized Scoring for Functional Aging

Modern healthcare is very good at diagnosing diseases. But aging is more than a list of diagnoses. A person may have controlled blood pressure, normal lab values, and no major illness, yet still be losing strength, balance, and independence. Today, there is no widely accepted standard for measuring overall functional aging. CHAP aims to fill this gap.


What Is Measured

Five Domains of Functional Aging

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Mobility

How well a person moves, walks, balances, and performs physical tasks.

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Strength

Physical reserve for daily activities, recovery, and independence.

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Cognition

How well a person thinks, remembers, focuses, and makes decisions.

Metabolic Health

Energy balance, glucose control, cardiovascular and metabolic function.

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Resilience

How well a person recovers from stress, illness, injury, or major life changes.


Functional Aging Assessment

A Practical Framework for Measuring Health

CHAP is developing a Functional Aging Assessment system, not to reduce aging to a single number, but to create a clear and useful profile of functional health.

Functional Aging Score

A composite measure of overall functional health across all five domains.

Functional Age

An estimate of how a person's performance compares with typical aging patterns.

Domain Scores

Separate scores for mobility, strength, cognition, metabolic health, and resilience.

Performance Ranking

Percentile rankings comparing a person's performance with others of similar age and sex.


Near-Term Goals

Building the Scientific Foundation

Functional Aging as a Standard of Medicine

Over time, CHAP aims to help establish functional aging as a recognized field of science and medicine, similar to how blood pressure, BMI, cholesterol, and HbA1c are used as standard measures today. A functional aging assessment can become an essential tool for a wide range of stakeholders.

Individuals

Understand your own aging trajectory and take informed action.

Families

Better support and plan care for older adults.

Clinicians

Monitor functional health and independence over time.

Researchers

Study aging biology and validate therapeutic interventions.

Industry

Develop aging-related therapies with meaningful functional endpoints.

Communities

Design better senior care systems grounded in functional data.

Longevity and Aging Signals

CHAP curates and monitors the latest scientific signals across aging, longevity, and healthspan research using RENKOM automated AI agents. Browse the full library of intelligently-selected papers and articles from leading journals and research institutions.

These Longevity and Aging Signals are curated in partnership with MicroMolar.

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Healthcare Research Briefs

These 200+ briefs covering the science of aging, interventions, metabolism, brain health, and more.

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